In the years since its inception in 1968, Boston Biomedical Research Institute (BBRI) has made many significant discoveries in basic science. Not only has BBRI made important contributions to the understanding of muscle contraction and of cell growth and motility, it has also contributed to the understanding of many of the basic mechanisms underlying diseases such as muscular dystrophy, cancer, diabetes, and Alzheimer's disease.

Over the past few years, it has become clear that small, independent research institutes like BBRI are likely to have difficulty remaining sustainable. As the result of BBRI's increasingly questionable financial viability and on the recommendation of the Board of Trustees, the members of BBRI's Corporation voted on November 15, 2012, to approve its dissolution as a not-for-profit corporation.

While the Institute will soon disappear as an entity, the science that has been conducted at BBRI will continue. Many of our scientists have found new research homes at excellent research organizations in the greater Boston area, including UMass Medical Center, Tufts University Medical School, Boston University School of Medicine, Massachusetts General Hospital and The Forsyth Institute, and several research institutions outside of the Greater Boston Area. We wish each of the scientists who has called BBRI home all possible success with their research going forward. Contributions from our generous donors have played a vital role in the discoveries that have taken place at BBRI. Our legacy of new understandings about smooth and striated muscle function, muscular dystrophy, diabetes, Alzheimer's disease, and cancer belongs in large measure to them. We are deeply appreciative of their generosity, as well as their friendship. We are also grateful to the many scientists, collaborators, administrators and others who helped to make these advances possible.

We are confident that many of the discoveries that have been made at BBRI will continue to shape science, long after its doors are shuttered. Thank you for your support over our 44 year history.

Chief Transition Officer
Jean Moses